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花色苷的结构中有多个酚羟基,属于羟基供体,它在植物组织中的主要作用是保护植物中易氧化的成分。相关科研工作者们一般都从评价其清除自由基能力、还原力、抑制脂质体过氧化能力、生物抗氧化效应等几个体系或动物体试验来检测抗氧化性.研究表明.花色苷类色素对羟自由基、超氧自由基 ...
  • In MCF-7L cells, insulin-like growth factor-I (IGF-I) stimulates activation of insulin receptor substrate-1 (IRS-1) and enhances cell proliferation. While others have shown that IGF-I enhances cell motility in MCF-7 cells, we have not been able to demonstrate this.
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    Sep 12, 2003 · MCF-7L cells were transiently transfected with the –47 RII-CAT construct containing either a wild type or mutated GC box along with a β-galactosidase plasmid for normalization of transfection efficiencies as described under “Experimental Procedures.” Cells were treated with TSA 4 h following transfection.
  • Dec 20, 2004 · Using an isogenic model of MCF-7 breast adenocarcinoma cells (MCF-7E and MCF-7L sublines that are sensitive and resistant to VD3 compounds), we found that VD3 compounds effectively downregulated...
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    However, in the TSA-treated MCF-7E cells ectopic Sp3 activated RII promoter. Histone acetyltransferase p300 was shown to acetylate Sp3. Sp3-mediated RII promoter activity was stimulated by wild type p300 but not the histone acetyltransferase domain-deleted mutant p300 in MCF-7L cells, suggesting the positive effect of p300 acetylase activity on ...
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    MCF-7 is a cell line that was first isolated in 1970 from the breast tissue of a 69-year old Caucasian woman. Of the two mastectomies she received, the first revealed that the removed tissue was benign.
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  • Jul 30, 2004 · MCF-7L cells were transiently transfected with the RI-Luc promoter reporter or control vector without RI promoter (PGL3) along with β-galactosidase plasmid for normalization of transfection efficiency as described under “Experimental Procedures.” The cells were harvested 24 h following SAHA treatment, and luciferase activity was determined ...
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    For MCF-7L cells, increasing power resulted in increased cell death (F=5.63, p=0.0018), and bare nanoshells caused more cell death than HER2-targeted nanoshells or laser treatment alone (F=30.13, p<0.001). For MCF-7/HER2-18 cells, death was greater with HER2-targeted nanoshells and was independent of laser power.Slab timber
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MCF-7L karyotyping and gene expression profiling have shown that these cells are consistent with the originally described cell line. T47D (parental cell line) was obtained from the ATCC in 1999 and maintained in MEM supplemented with 5% FBS, 1× nonessential amino acids, and 1 nmol/L insulin.
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MCF-7L cells, an ER+cell line, were provided by C. Kent Osborne (Baylor College of Medicine) and ER-MDA-MB-435, LCC6 (a metastatic sub-line of the MDA-MB-435 cells) and MDA-MB-231 cells were provided by Robert Clarke (Lombardi Cancer Center, Georgetown University, Washington, DC, USA). In preclinical studies, Harris and colleagues transplanted mice with a human estrogen receptor- positive breast cancer cell line called MCF-7L and then treated the mice with tamoxifen.

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